Acute blood loss anemia aggravates endothelial dysfunction after acute myocardial infarction
After AMI, acute anemia is associated with ROS-mediated severe endothelial dysfunction, which is partly mediated by RBCs. Antioxidant supplementation with NAC is a potential therapeutic option to reverse the severe ED in anemia following AMI.
Authors
- Stefanie Becher
- Norbert Gerdes (ORCID: https://orcid.org/0000-0002-4546-7208)
- Malte Kelm (ORCID: https://orcid.org/0000-0003-0060-1052)
- Aslıhan Şahin (ORCID: https://orcid.org/0000-0002-2082-3907)
- Christian Jung (ORCID: https://orcid.org/0000-0001-8325-250X)
- Amin Polzin (ORCID: https://orcid.org/0000-0002-5891-9672)
- Mohammed Rabiul Hosen (ORCID: https://orcid.org/0000-0003-2823-0628)
- Amira El
- Ramesh Chennupati (ORCID: https://orcid.org/0000-0002-3994-5285)
- Isabella Solga
- Patricia Wischmann (ORCID: https://orcid.org/0000-0002-7442-6915)
- Vithya Yogathasan
- Lina Hofer
- Feyza Gül Celik
Institutions
- University Hospital Bonn (DE)
- Düsseldorf University Hospital (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-10-13
- DOI
- https://doi.org/10.3389/fcvm.2025.1635293
- Primary Topic
- Acute Myocardial Infarction Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00