Comparison of interrupted and continuous modulator therapy in cystic fibrosis: a real life experience in Turkey
Short-term clinical outcomes in ppFEV₁ and BMI were similar between continuous and intermittent treatment. However, treatment interruptions may reduce cumulative benefits, potentially impacting long-term outcomes. Ensuring uninterrupted access to HEMT is essential, especially in low- and middle-income countries<b>.</b>
Authors
- Tuğba Şişmanlar Eyüboğlu (ORCID: https://orcid.org/0000-0001-7284-4999)
- Yakup Canıtez (ORCID: https://orcid.org/0000-0001-8929-679X)
- Esen Demir (ORCID: https://orcid.org/0000-0003-2736-8924)
- Cansu Altuntaş (ORCID: https://orcid.org/0000-0002-1161-5145)
- Merve Selçuk (ORCID: https://orcid.org/0000-0002-2146-3966)
- Gülay Bayramoğlu (ORCID: https://orcid.org/0000-0002-3835-9399)
- Yasemi̇n Gökdemi̇r (ORCID: https://orcid.org/0000-0002-0853-7932)
- Veysel Karakulak (ORCID: https://orcid.org/0000-0002-1858-5647)
- Fazi̇let Karakoç (ORCID: https://orcid.org/0000-0001-8518-4715)
- Erkan Çakır (ORCID: https://orcid.org/0000-0002-1438-7854)
- Gökçen Ünal (ORCID: https://orcid.org/0000-0002-4380-7643)
- Abdurrahman Erdem Başaran (ORCID: https://orcid.org/0000-0002-9092-6936)
- Ela Erdem Eralp (ORCID: https://orcid.org/0000-0001-8829-3431)
- Salih Uytun (ORCID: https://orcid.org/0000-0002-7301-3692)
- Sinem Can Oksay (ORCID: https://orcid.org/0000-0001-9801-3181)
- Mehmet Köse (ORCID: https://orcid.org/0000-0002-3003-918X)
- Bulent Taner Karadag (ORCID: https://orcid.org/0000-0003-0605-8871)
- Sedat Öktem (ORCID: https://orcid.org/0000-0002-7950-2067)
- Velat Şen (ORCID: https://orcid.org/0000-0002-8411-4499)
- Pınar Ergenekon (ORCID: https://orcid.org/0000-0003-0228-9832)
- Zeynep Seda Uyan (ORCID: https://orcid.org/0000-0002-7540-3467)
- Sevgi Pekcan (ORCID: https://orcid.org/0000-0002-8059-902X)
Institutions
- Dicle University (TR)
- Bursa Uludağ Üni̇versi̇tesi̇ (TR)
- Koç University (TR)
- Akdeniz University (TR)
- Istanbul Medipol University (TR)
- Ege University (TR)
- Necmettin Erbakan University (TR)
- Istinye University (TR)
- Başkent University Hospital (TR)
- Cukurova University (TR)
- Istanbul Medeniyet University (TR)
- Marmara University (TR)
- Erciyes University (TR)
- Gazi University (TR)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-10-13
- DOI
- https://doi.org/10.3389/fped.2025.1659633
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00