Laboratory and imaging risk factors for mortality in children with primary hemophagocytic lymphohistiocytosis

No significant differences in mortality risk were found between p-HLH and s-HLH or among p-HLH subtypes. For p-HLH, severe liver/spleen damage and pleural effusion emerged as key mortality predictors.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-10-13
DOI
https://doi.org/10.3389/fonc.2025.1668762
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
Field-Weighted Citation Impact
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article

Laboratory and imaging risk factors for mortality in children with primary hemophagocytic lymphohistiocytosis

Wei Ma, Rui Tang, Sijie Gao, Yan Huang et al.
Frontiers in Oncology
Autoimmune and Inflammatory Disorders Research
article

Laboratory and imaging risk factors for mortality in children with primary hemophagocytic lymphohistiocytosis

Wei Ma, Rui Tang, Sijie Gao, Yan Huang, Xiao Li, Wei Li, Jia Huang, Hailun Peng, Chundan Gong, Sipei Xu
article en

Abstract

No significant differences in mortality risk were found between p-HLH and s-HLH or among p-HLH subtypes. For p-HLH, severe liver/spleen damage and pleural effusion emerged as key mortality predictors.

Frontiers in OncologyVol. 15
China International Science and Technology Cooperation (CN), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Children's Hospital of Chongqing Medical University (CN), First People's Hospital of Chongqing (CN), Chongqing Dazu District People's Hospital (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 63%
Autoimmune and Inflammatory Disorders Research
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