Comparative effectiveness and safety of tenecteplase versus alteplase for intravenous thrombolysis in acute ischemic stroke: a retrospective study
Tenecteplase demonstrated comparable safety and functional outcomes to alteplase, with signals of potential benefit in patients with more severe strokes. These findings reinforce trial evidence supporting tenecteplase as a practical and effective alternative to alteplase.
Authors
- Feng Zhang (ORCID: https://orcid.org/0000-0002-7845-7970)
- Weili Zhao (ORCID: https://orcid.org/0000-0001-9403-1382)
- Ruijie Zhao (ORCID: https://orcid.org/0000-0003-2204-7996)
- Yalin Liu (ORCID: https://orcid.org/0000-0003-0337-6380)
- Yang Zhao (ORCID: https://orcid.org/0000-0003-2247-8286)
Institutions
- Hebei Medical University (CN)
- Xingtai People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-10-13
- DOI
- https://doi.org/10.3389/fneur.2025.1691168
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 1.35