Mediation analysis for integrating motor symptoms of Parkinson’s disease, cognitive function, and gait characteristics
The results indicated that, when analyzing plantar dorsiflexion angle and swing phase symmetry in PD patients, the influence of motor symptoms was dominant; when analyzing stride length, motor symptoms and cognitive function need to be considered simultaneously; when analyzing velocity, the influence of motor symptoms and age should be focused on.
Authors
- Ruichen Liu (ORCID: https://orcid.org/0000-0002-1631-9652)
- Wenchao Yin (ORCID: https://orcid.org/0009-0001-0442-7752)
- Cui Wang (ORCID: https://orcid.org/0000-0002-8070-5574)
- Hong Gao (ORCID: https://orcid.org/0000-0002-3469-7526)
- Yue Liu (ORCID: https://orcid.org/0000-0002-3622-6728)
- Chenxin Shen
Institutions
- Dalian University of Technology (CN)
- Dalian Municipal Central Hospital (CN)
- Shenyang Fifth People Hospital (CN)
- Shenyang Fire Research Institute (CN)
- Dalian Maritime University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-10-13
- DOI
- https://doi.org/10.3389/fneur.2025.1659581
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Dalian University of Technology