Determination of Azoxystrobin and Copper Residues in Labeo rohita Individually and in Combination along with the Use of Activated Charcoal

This research aims to understand the toxic impact of the fungicide Azoxystrobin and the heavy metal Copper on the freshwater fish Rohu (Labeo rohita) and potential role of activated charcoal in mitigating their effects. In the present study the experimental fish used as an analytical matrix for residue analysis of selected toxicants. These are affecting every aspect of fish physiology, including biochemical, histology, haematology and behaviour. The data represents maximum amount of copper residues found in the liver tissues of 1 day lethal and 14 days sublethal exposures but in the case of 1day sublethal exposures the maximum residues were noticed in intestine except in the liver of AZ-CS exposure. In this study tissue specific bioconcentration was observed for Azoxystrobin and copper in intestine, liver, and Kidney. The lower residues were found in in the combination of activated charcoal exposures due to their ability to bind the conjugated drug.