Identification of specific molecular markers in severe heatstroke using transcriptomics techniques
This study provides comparative transcriptomic evidence distinguishing heatstroke from fever. The identified markers, particularly Hspa1a, Hspa1b, Cyp7a1, Arrdc3, and G6pc, may serve as potential forensic indicators for differentiating hyperthermia-related deaths, while also offering new insights into the molecular responses underlying heat stress and fever.
Authors
- Yun-chao Zhou (ORCID: https://orcid.org/0009-0000-6007-2362)
- Yu-zhao Xu
- Jianghuan Lu
- Zhongping Duan (ORCID: https://orcid.org/0000-0002-2188-9692)
- Mei Wang (ORCID: https://orcid.org/0000-0001-8352-2477)
- Jianhua Chen (ORCID: https://orcid.org/0000-0002-7129-8639)
- Hui Liu (ORCID: https://orcid.org/0000-0003-0578-4062)
- Jianqiang Deng
- Yixin Ma
Institutions
- Third Affiliated Hospital of Southern Medical University (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- International Journal of Legal Medicine
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1007/s00414-025-03634-8
- Citations
- 1
- Primary Topic
- Climate Change and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- Hainan Medical University