IDH1 mutated prostate cancer with psammomatous calcifications: A case report and review of the literature

We report a case of grade group 2, pT 3 N0 Mx prostate acinar adenocarcinoma with intratumoural psammomatous calcifications and IDH1 mutation. This is an emerging molecular subtype of prostate cancer associated with a propensity for higher grade and stage of disease. The index case was of intermediate grade but had locally advanced stage III disease.

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Publication Details

Journal
Human Pathology Reports
Published
2025-10-12
DOI
https://doi.org/10.1016/j.hpr.2025.300800
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

IDH1 mutated prostate cancer with psammomatous calcifications: A case report and review of the literature

Pamela S. Gaskin, David A. Gaskin, N. Depeiza, Ann Reid et al.
Human Pathology Reports
Prostate Cancer Treatment and Research
article

IDH1 mutated prostate cancer with psammomatous calcifications: A case report and review of the literature

Pamela S. Gaskin, David A. Gaskin, N. Depeiza, Ann Reid, Jeetu Nebhnani
article en

Abstract

We report a case of grade group 2, pT 3 N0 Mx prostate acinar adenocarcinoma with intratumoural psammomatous calcifications and IDH1 mutation. This is an emerging molecular subtype of prostate cancer associated with a propensity for higher grade and stage of disease. The index case was of intermediate grade but had locally advanced stage III disease.

Human Pathology ReportsVol. 42
Barbados Community College (BB), University of the West Indies (BB), Queen Elizabeth Hospital (BB)
Openalex Percentile: Top 59%
Prostate Cancer Treatment and Research
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