The Association Between HbA1c Level and the Outcomes of Rotator Cuff Repair Surgery in Patients Managed at a Tertiary Center: A Retrospective Cohort Study

Background Rotator cuff tears are a leading cause of shoulder dysfunction and often require surgical repair. Diabetes mellitus can impair tendon healing through chronic inflammation and poor glycemic control, reflected by elevated glycated hemoglobin (HbA1c) levels. This study aimed to explore the association between HbA1c levels and the outcomes of rotator cuff repair surgery in patients managed at a tertiary center. Methodology This retrospective cohort study was conducted at King Abdulaziz Medical City, Riyadh, Saudi Arabia, from February 2020 to February 2025. Data were collected on demographics, pre- and postoperative details, outcomes, and comorbidities. Data were analyzed using Fisher's exact test, Spearman's correlation, independent-sample t-tests, and descriptive statistics, conducted using SPSS version 29.0.0 (IBM Corp., Armonk, NY, USA). Results Of the 79 eligible patients, 38 were excluded due to incomplete HbA1c data, and 41 were analyzed. Most patients were female (28; 68.3%) with a mean age of 57.1 ± 7.6 years (range = 39-69 years). The average body mass index was 30.2 ± 4.3 kg/m², with 18 (43.9%) patients classed as overweight and 19 (46.3%) obese. Common comorbidities included dyslipidemia (32; 78.0%), hypertension (23; 56.1%), and diabetes (21; 51.2%). Preoperative HbA1c showed no correlation with functional improvements in abduction (r = 0.132, p = 0.455), forward flexion (r = -0.082, p = 0.646), external rotation (r = 0.292, p = 0.187), or return to work (r = 0.008, p = 0.961). Complication rates were similar between controlled (6; 66.7%) and uncontrolled (3; 33.3%) HbA1c groups (p = 0.707). Hypertension (B = 1.327, p = 0.032) and liver disease (B = 3.913, p = 0.009) predicted higher postoperative HbA1c, while other comorbidities showed no significant associations. Conclusions Preoperative HbA1c was not associated with postoperative functional outcomes or complications. However, certain comorbidities were linked to higher postoperative HbA1c, suggesting that overall health conditions may influence recovery more than glycemic control alone. These findings highlight the importance of comprehensive perioperative assessment and tailored management strategies to optimize outcomes in rotator cuff repair patients.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2025-10-12
DOI
https://doi.org/10.7759/cureus.94387
Primary Topic
Shoulder Injury and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

The Association Between HbA1c Level and the Outcomes of Rotator Cuff Repair Surgery in Patients Managed at a Tertiary Center: A Retrospective Cohort Study

Omar F. Alsalem, Ahmed AlHussain, Ziad A Aljaafri, Talal Hussain Binmushayt et al.
Cureus
Shoulder Injury and Treatment
article

The Association Between HbA1c Level and the Outcomes of Rotator Cuff Repair Surgery in Patients Managed at a Tertiary Center: A Retrospective Cohort Study

Omar F. Alsalem, Ahmed AlHussain, Ziad A Aljaafri, Talal Hussain Binmushayt, Abdullah Alghamdi, Abdulaziz Ghazi Alotaibi
article en

Abstract

Background Rotator cuff tears are a leading cause of shoulder dysfunction and often require surgical repair. Diabetes mellitus can impair tendon healing through chronic inflammation and poor glycemic control, reflected by elevated glycated hemoglobin (HbA1c) levels. This study aimed to explore the association between HbA1c levels and the outcomes of rotator cuff repair surgery in patients managed at a tertiary center. Methodology This retrospective cohort study was conducted at King Abdulaziz Medical City, Riyadh, Saudi Arabia, from February 2020 to February 2025. Data were collected on demographics, pre- and postoperative details, outcomes, and comorbidities. Data were analyzed using Fisher's exact test, Spearman's correlation, independent-sample t-tests, and descriptive statistics, conducted using SPSS version 29.0.0 (IBM Corp., Armonk, NY, USA). Results Of the 79 eligible patients, 38 were excluded due to incomplete HbA1c data, and 41 were analyzed. Most patients were female (28; 68.3%) with a mean age of 57.1 ± 7.6 years (range = 39-69 years). The average body mass index was 30.2 ± 4.3 kg/m², with 18 (43.9%) patients classed as overweight and 19 (46.3%) obese. Common comorbidities included dyslipidemia (32; 78.0%), hypertension (23; 56.1%), and diabetes (21; 51.2%). Preoperative HbA1c showed no correlation with functional improvements in abduction (r = 0.132, p = 0.455), forward flexion (r = -0.082, p = 0.646), external rotation (r = 0.292, p = 0.187), or return to work (r = 0.008, p = 0.961). Complication rates were similar between controlled (6; 66.7%) and uncontrolled (3; 33.3%) HbA1c groups (p = 0.707). Hypertension (B = 1.327, p = 0.032) and liver disease (B = 3.913, p = 0.009) predicted higher postoperative HbA1c, while other comorbidities showed no significant associations. Conclusions Preoperative HbA1c was not associated with postoperative functional outcomes or complications. However, certain comorbidities were linked to higher postoperative HbA1c, suggesting that overall health conditions may influence recovery more than glycemic control alone. These findings highlight the importance of comprehensive perioperative assessment and tailored management strategies to optimize outcomes in rotator cuff repair patients.

CureusVol. 17(10)
King Saud bin Abdulaziz University for Health Sciences (SA), King Abdulaziz Medical City (SA)
Openalex Percentile: Top 55%
Shoulder Injury and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.