PHARMACO-EEG-BASED CLASSIFICATION OF PSYCHOTROPIC ACTIVITY OF A NOVEL CHROMONE-CONTAINING ALLYLMORPHOLINE IN RATS
The data obtained confirm the effectiveness of the combined use of NBC and PCA for classification tasks. The effects of the different doses of compound 33a on ECoG, as well as the abolition of the effects of apomorphine and 5-HTP in mice and rats, suggest a dopamine- and 5-HT2-blocking action of the molecule under study.
Authors
- E. S. Fedorova (ORCID: https://orcid.org/0000-0002-5774-7901)
- N A Petrov (ORCID: https://orcid.org/0000-0001-9755-6002)
- Yuriy I. Sysoev (ORCID: https://orcid.org/0000-0003-4199-5318)
- Н. С. Курмазов (ORCID: https://orcid.org/0000-0001-7212-6903)
- Maria Puchik
- N. M. Chernov (ORCID: https://orcid.org/0000-0003-1278-8109)
- D. D. Shits
- Sergey Chervonetskiy
- Sergey V. Okovityi
Institutions
- St Petersburg University (RU)
- Saint - Petersburg State Chemical Pharmaceutical Academy (RU)
- Institute of the Human Brain (RU)
- Pavlov Institute of Physiology of the Russian Academy of Sciences (RU)
Publication Details
- Journal
- Advanced Pharmaceutical Bulletin
- Published
- 2025-10-11
- DOI
- https://doi.org/10.34172/apb.025.45140
- Primary Topic
- Synthesis of Organic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Saint Petersburg State University
- Russian Science Foundation
- Russian Academy of Sciences