[Obstructive sleep apnea and cardiovascular disease management: re-exploring the role and clinical indications of continuous positive airway pressure].

Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular disease (CVD). Although continuous positive airway pressure (CPAP) is the first-line treatment for OSA, its role in primary and secondary prevention of CVD remains controversial. This review explored the potential mechanisms, key evidence, and inconsistent outcomes of CPAP intervention in the context of OSA-related CVD. By incorporating insights into OSA subtypes, novel physiological markers, and practical clinical challenges, we revisited the indications for CPAP therapy. Ultimately, we emphasized the need to reassess CPAP indications based on individualized risk profiles to promote more precise and effective management of OSA-related cardiovascular risks.

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Publication Details

Journal
PubMed
Published
2025-10-12
DOI
https://doi.org/10.3760/cma.j.cn112147-20250225-00108
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
0.00
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article

[Obstructive sleep apnea and cardiovascular disease management: re-exploring the role and clinical indications of continuous positive airway pressure].

Xiangyi Hui, Yi Xiao
PubMed
Obstructive Sleep Apnea Research
article

[Obstructive sleep apnea and cardiovascular disease management: re-exploring the role and clinical indications of continuous positive airway pressure].

Xiangyi Hui, Yi Xiao
article en

Abstract

Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular disease (CVD). Although continuous positive airway pressure (CPAP) is the first-line treatment for OSA, its role in primary and secondary prevention of CVD remains controversial. This review explored the potential mechanisms, key evidence, and inconsistent outcomes of CPAP intervention in the context of OSA-related CVD. By incorporating insights into OSA subtypes, novel physiological markers, and practical clinical challenges, we revisited the indications for CPAP therapy. Ultimately, we emphasized the need to reassess CPAP indications based on individualized risk profiles to promote more precise and effective management of OSA-related cardiovascular risks.

PubMedVol. 48(10)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
Openalex Percentile: Top 64%
Obstructive Sleep Apnea Research
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[Obstructive sleep apnea and cardiovascular disease management: re-exploring the role and clinical indications of continuous positive airway pressure]. — Xiangyi Hui, Yi Xiao · PubMed (2025) | TGRS Research Map | TGRS