[Pulmonary involvement of intravascular large B-cell lymphoma: a case report].

Intravascular large B-cell lymphoma (IVLBCL) represents a rare subtype of extranodal lymphoma characterized by the proliferation of B-cells within the lumen of blood vessels. Pulmonary involvement occurs in approximately 60% of cases. Diagnosis of IVLBCL can be challenging as the clinical manifestations are usually nonspecific. We report a case of IVLBCL presenting with fever and dyspnea. CT scan revealed bilateral diffuse pulmonary ground-glass opacities with gravity-dependent distribution. The diagnosis was established through transbronchial lung biopsy. This case report aimed to heighten clinical awareness and sharpen diagnostic skills regarding pulmonary involvement in IVLBCL.

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Publication Details

Journal
PubMed
Published
2025-10-12
DOI
https://doi.org/10.3760/cma.j.cn112147-20250517-00269
Primary Topic
CNS Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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[Pulmonary involvement of intravascular large B-cell lymphoma: a case report].

Kai‐Feng Xu, Wendy Y. Cheng, H Huang, Congwei Jia et al.
PubMed
CNS Lymphoma Diagnosis and Treatment
article

[Pulmonary involvement of intravascular large B-cell lymphoma: a case report].

Kai‐Feng Xu, Wendy Y. Cheng, H Huang, Congwei Jia, Yujun Shi, Chen Wang, Chuan Shi, Wei J. Wang
article en

Abstract

Intravascular large B-cell lymphoma (IVLBCL) represents a rare subtype of extranodal lymphoma characterized by the proliferation of B-cells within the lumen of blood vessels. Pulmonary involvement occurs in approximately 60% of cases. Diagnosis of IVLBCL can be challenging as the clinical manifestations are usually nonspecific. We report a case of IVLBCL presenting with fever and dyspnea. CT scan revealed bilateral diffuse pulmonary ground-glass opacities with gravity-dependent distribution. The diagnosis was established through transbronchial lung biopsy. This case report aimed to heighten clinical awareness and sharpen diagnostic skills regarding pulmonary involvement in IVLBCL.

PubMedVol. 48(10)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
Openalex Percentile: Top 59%
CNS Lymphoma Diagnosis and Treatment
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