[Treatable traits associated with acute exacerbations of bronchiectasis].

Exacerbations of bronchiectasis are heterogeneous events characterized by worsening symptoms and increased infection. These episodes impair patients' quality of life and increase mortality. They also serve as crucial indicators when monitoring disease progression and assessing therapeutic interventions. The Treatable traits' strategy is a model of care that targets multiple modifiable characteristics to deliver precision medicine and improve clinical prognosis. This study focuses on treatable traits including respiratory infections, airway inflammation, respiratory symptoms, comorbidities, underlying aetiologies, and behavioural or lifestyle factors. It examines their association with bronchiectasis exacerbations, with the aim of enabling the clinical implementation of this framework for reducing exacerbation frequency.

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Publication Details

Journal
PubMed
Published
2025-10-12
DOI
https://doi.org/10.3760/cma.j.cn112147-20250302-00120
Primary Topic
Cystic Fibrosis Research Advances
Type
article
Field-Weighted Citation Impact
0.00
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article

[Treatable traits associated with acute exacerbations of bronchiectasis].

B.R. Zhao, Sheng Xia, Y Y Li, Chengping Hu et al.
PubMed
Cystic Fibrosis Research Advances
article

[Treatable traits associated with acute exacerbations of bronchiectasis].

B.R. Zhao, Sheng Xia, Y Y Li, Chengping Hu, Tiezhu Li
article en

Abstract

Exacerbations of bronchiectasis are heterogeneous events characterized by worsening symptoms and increased infection. These episodes impair patients' quality of life and increase mortality. They also serve as crucial indicators when monitoring disease progression and assessing therapeutic interventions. The Treatable traits' strategy is a model of care that targets multiple modifiable characteristics to deliver precision medicine and improve clinical prognosis. This study focuses on treatable traits including respiratory infections, airway inflammation, respiratory symptoms, comorbidities, underlying aetiologies, and behavioural or lifestyle factors. It examines their association with bronchiectasis exacerbations, with the aim of enabling the clinical implementation of this framework for reducing exacerbation frequency.

PubMedVol. 48(10)
Central South University (CN), Xiangya Hospital Central South University (CN)
Openalex Percentile: Top 59%
Cystic Fibrosis Research Advances
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[Treatable traits associated with acute exacerbations of bronchiectasis]. — B.R. Zhao, Sheng Xia, et al. · PubMed (2025) | TGRS Research Map | TGRS