Is Local Anaesthetic Drug Allergy Really Common? Single Centre Experience

Objective: The main aim of this study is to objectively determine the actual frequency of allergic reactions in patients with a history of allergy to local anaesthetic drugs using skin tests and alternative provocation tests. In addition, it is aimed to evaluate the prevalence of other drug allergies in individuals presenting with local anaesthetic allergy and the effect of this on clinical presentation. The study also aims to shed light on clinical approaches by analysing the test results performed in patients who are administered alternative drugs due to a history of allergy. Methods: The data of patients who presented to the immunology and allergy outpatient clinic with local anaesthetic agent allergy between 01.01.2019-01.04.2025 were retrospectively reviewed. Other drug reactions, local anaesthetic agent allergy severity and alternative drug test results were recorded. Conclusion: It was observed that the majority of the patients described reactions with drugs other than local anaesthetics and therefore consulted a doctor. This situation, in accordance with the literature, showed that the reason for the application of both health professionals and patients was not due to local allergic drug allergy. The fact that only two patients were positive in the tests performed shows that the rate of local anaesthetic allergy is low, although the number of patients is insufficient.