Association between local gray matter volume differences and stereo‐electroencephalography‐defined epileptogenicity

Local GMV differences were positively associated with EZ contacts in the whole cohort and MRI-positive patients but not in MRI-negative patients, with positive associations in the neocortex and a negative one in the mesiotemporal structures. Within MRI-visible lesions, increased GMV was associated with EZ contacts.

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Publication Details

Journal
Epilepsia
Published
2025-10-11
DOI
https://doi.org/10.1111/epi.18671
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
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Association between local gray matter volume differences and stereo‐electroencephalography‐defined epileptogenicity

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Association between local gray matter volume differences and stereo‐electroencephalography‐defined epileptogenicity

Terence John O'Brien, Parveen Sagar, Joshua Laing, Thanomporn Wittayacharoenpong, Meng Law, Mohammad‐Reza Nazem‐Zadeh, Matthew Gutman, Benjamin Sinclair, Patrick Kwan, Jacob Bunyamin, Andrew Neal, Noam Bosak, Zhibin Chen, Martin Hunn
article en

Abstract

Local GMV differences were positively associated with EZ contacts in the whole cohort and MRI-positive patients but not in MRI-negative patients, with positive associations in the neocortex and a negative one in the mesiotemporal structures. Within MRI-visible lesions, increased GMV was associated with EZ contacts.

EpilepsiaVol. 67(2)
Alfred Health (AU), Monash University (AU)
Openalex Percentile: Top 65%
Epilepsy research and treatment
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