Clinical utility of direct disk diffusion testing in guiding antibiotic therapy for gram-negative bacteremia
Direct disk diffusion testing (dDDT) for Gram-negative bacteremia significantly shortens susceptibility reporting, improves antibiotic appropriateness, and may guide antibiotic stewardship. While a trend towards lower mortality was observed, dDDT was not an independent predictor of survival in this study.
Authors
- King‐Pui Florence Chan (ORCID: https://orcid.org/0000-0003-2094-1206)
- Vincent Chi‐Chung Cheng (ORCID: https://orcid.org/0000-0003-1765-7706)
- Kelvin Hei‐Yeung Chiu (ORCID: https://orcid.org/0000-0003-2456-3943)
- Pak‐Leung Ho (ORCID: https://orcid.org/0000-0002-8811-1308)
- Ting Fung (ORCID: https://orcid.org/0000-0001-6028-5640)
- Edwin Kwan-Yeung Chiu (ORCID: https://orcid.org/0000-0003-1644-491X)
- Xin Li (ORCID: https://orcid.org/0000-0001-8948-6331)
- Simon Yung-Chun So (ORCID: https://orcid.org/0009-0008-7366-5114)
Institutions
- Department of Health (CN)
- University of South Carolina (US)
- Queen Mary Hospital (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-10-11
- DOI
- https://doi.org/10.1016/j.ijid.2025.108127
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 0.00