Contralateral neurofluid dynamics predict survival in IDH wild-type glioblastoma: A DTI-ALPS and free water imaging study
Neurofluid dynamic alterations in the contralateral hemisphere, assessed using DTI-ALPS and FW imaging, were independently associated with survival in patients with IDH wild-type GBM. These findings support the use of glymphatic imaging markers for prognostic stratification and therapeutic targeting.
Authors
- Kaito Takabayashi (ORCID: https://orcid.org/0000-0002-5562-1504)
- Kanako K. Kumamaru (ORCID: https://orcid.org/0000-0001-5924-3283)
- Akifumi Hagiwara (ORCID: https://orcid.org/0000-0001-5277-3249)
- Akihiko Wada (ORCID: https://orcid.org/0000-0003-3432-0267)
- Benjamin M. Ellingson (ORCID: https://orcid.org/0000-0002-2764-6640)
- Koji Kamagata
- Christina Andica (ORCID: https://orcid.org/0000-0002-9339-6950)
- Junko Kikuta (ORCID: https://orcid.org/0000-0003-1324-8614)
- Akihide Kondo (ORCID: https://orcid.org/0000-0003-1729-4490)
- Osamu Akiyama (ORCID: https://orcid.org/0000-0001-9662-2530)
- Toshiaki Akashi (ORCID: https://orcid.org/0000-0002-3056-0792)
- Wataru Uchida (ORCID: https://orcid.org/0000-0002-8453-1532)
- Takuya Ozawa
- Rui Zou (ORCID: https://orcid.org/0000-0002-3918-9010)
- Shigeki Aoki (ORCID: https://orcid.org/0000-0003-2821-0651)
Institutions
- University of California, Los Angeles (US)
- Juntendo University (JP)
- University of Tokyo Hospital (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- Neuro-Oncology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1093/neuonc/noaf242
- Citations
- 1
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.91