Shared and distinct metabolomics profiles associated with microvascular complications in the Diabetes Prevention Program Outcomes Study
The existence of distinct metabolite profiles associated with single microvascular complications highlights the importance of characterising pathophysiological mechanisms specific to each complication, in addition to studying shared mechanisms across multiple complications.
Authors
- David M. Nathan (ORCID: https://orcid.org/0000-0003-2503-2650)
- José A. Luchsinger (ORCID: https://orcid.org/0000-0002-5886-3648)
- Roeland J.W. Middelbeek (ORCID: https://orcid.org/0000-0003-3862-8082)
- Marinella Temprosa (ORCID: https://orcid.org/0000-0002-9976-745X)
- Wei Perng (ORCID: https://orcid.org/0000-0001-8552-6850)
- Robert E. Gerszten (ORCID: https://orcid.org/0000-0002-6767-7687)
- William C. Knowler (ORCID: https://orcid.org/0000-0002-7004-5197)
- Steven E. Kahn (ORCID: https://orcid.org/0000-0001-7307-9002)
- Shiyu Shu (ORCID: https://orcid.org/0000-0001-9539-5196)
- Dana Dabelea (ORCID: https://orcid.org/0000-0001-9514-8929)
Institutions
- Joslin Diabetes Center (US)
- Milken Institute (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Colorado School of Public Health (US)
- George Washington University (US)
- University of Washington (US)
- Columbia University Irving Medical Center (US)
- Massachusetts General Hospital (US)
- VA Puget Sound Health Care System (US)
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- Diabetologia
- Published
- 2025-10-11
- DOI
- https://doi.org/10.1007/s00125-025-06571-8
- Citations
- 1
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.81