Shared and distinct neural signatures in major depressive disorder and comorbid post-traumatic stress disorder: Insights from structural and functional imaging
This study uncovers shared and distinct neural signatures in MDD and MDD-PTSD, offering potential biomarkers for targeted interventions. These findings deepen our understanding of the neural basis of trauma-related psychiatric disorders and suggest potential new avenues for precision medicine in MDD and PTSD.
Authors
- Lanying Liu (ORCID: https://orcid.org/0000-0002-2788-071X)
- Li-Yuan Guo
- Liyuan Luo (ORCID: https://orcid.org/0000-0002-8729-6128)
- Qing Wang (ORCID: https://orcid.org/0000-0002-6843-5516)
- Huichao Li (ORCID: https://orcid.org/0000-0002-3645-5379)
Institutions
- Zhejiang Chinese Medical University (CN)
- Shanghai Mental Health Center (CN)
- Tongde Hospital of Zhejiang Province (CN)
Publication Details
- Journal
- Journal of Affective Disorders
- Published
- 2025-10-11
- DOI
- https://doi.org/10.1016/j.jad.2025.120414
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00