Evaluation of the Application Value of Optogenetics Technology in the Development of Immunotherapy Methods for Tumors

In the field of tumor treatment, traditional methods have limitations, and tumor immunotherapy has become an important direction. As a cutting-edge discipline, optogenetics has been widely explored for application in tumor immunotherapy, such as regulating the activity of immune cells and influencing the tumor-related nervous system. However, there are still deficiencies in the application of this technology in tumor immunotherapy, such as the specific expression of photosensitive proteins and the precise delivery of light in vivo, which have not yet been resolved. This focuses the core mechanisms of optogenetic technology, elaborates in detail on its applications and research progress in regulating tumor immune cells such as T cells and macrophages, as well as improving the tumor microenvironment, and explores the prospects of its combined application with other tumor treatment technologies. The results indicate that optogenetic technology holds great potential in the development of tumor immunotherapy methods. The prospects. The results show that optogenetic technology has great potential in the development of tumor immunotherapy methods. This study provides new theoretical and practical references for tumor immunotherapy. In the future, technical challenges need to be further overcome. Subsequent research can focus on optimizing the expression of photosensitive proteins and the light delivery system, etc., to promote the application and development of optogenetic technology in tumor immunotherapy.

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Publication Details

Journal
Transactions on Materials Biotechnology and Life Sciences
Published
2025-10-11
DOI
https://doi.org/10.62051/e15j8a18
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
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article

Evaluation of the Application Value of Optogenetics Technology in the Development of Immunotherapy Methods for Tumors

Huishan Chen
Transactions on Materials Biotechnology and Life Sciences
CAR-T cell therapy research
article

Evaluation of the Application Value of Optogenetics Technology in the Development of Immunotherapy Methods for Tumors

Huishan Chen
article en

Abstract

In the field of tumor treatment, traditional methods have limitations, and tumor immunotherapy has become an important direction. As a cutting-edge discipline, optogenetics has been widely explored for application in tumor immunotherapy, such as regulating the activity of immune cells and influencing the tumor-related nervous system. However, there are still deficiencies in the application of this technology in tumor immunotherapy, such as the specific expression of photosensitive proteins and the precise delivery of light in vivo, which have not yet been resolved. This focuses the core mechanisms of optogenetic technology, elaborates in detail on its applications and research progress in regulating tumor immune cells such as T cells and macrophages, as well as improving the tumor microenvironment, and explores the prospects of its combined application with other tumor treatment technologies. The results indicate that optogenetic technology holds great potential in the development of tumor immunotherapy methods. The prospects. The results show that optogenetic technology has great potential in the development of tumor immunotherapy methods. This study provides new theoretical and practical references for tumor immunotherapy. In the future, technical challenges need to be further overcome. Subsequent research can focus on optimizing the expression of photosensitive proteins and the light delivery system, etc., to promote the application and development of optogenetic technology in tumor immunotherapy.

Transactions on Materials Biotechnology and Life SciencesVol. 8
Ocean University of China (CN)
Openalex Percentile: Top 61%
CAR-T cell therapy research
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