Disitamab vedotin plus programmed death-1 inhibitor for pre-treated HER2 overexpressed advanced gastric cancer: a multicentre retrospective real-world study

RC48 plus PD-1 inhibitor for pre-treated advanced G/GEJC patients with HER2 2+/3+ demonstrated superior efficacy than RC48 monotherapy and favourable safety. This combination represents a potential therapeutic strategy, but further large-scale prospective studies are still needed.

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Publication Details

Journal
Annals of Medicine
Published
2025-10-11
DOI
https://doi.org/10.1080/07853890.2025.2569994
Citations
2
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
3.04
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article

Disitamab vedotin plus programmed death-1 inhibitor for pre-treated HER2 overexpressed advanced gastric cancer: a multicentre retrospective real-world study

Fengping Li, Ming-Yu Lai, Min Lai, Tsao‐Cheng Huang et al.
2 citations
Annals of Medicine
Gastric Cancer Management and Outcomes
3.04
article

Disitamab vedotin plus programmed death-1 inhibitor for pre-treated HER2 overexpressed advanced gastric cancer: a multicentre retrospective real-world study

Fengping Li, Ming-Yu Lai, Min Lai, Tsao‐Cheng Huang, Zhiwei Li, Kaobin Ouyang, Huayuan Liang, Miao‐Zhen Qiu, Rou Zhong, Zhong Xie, Liying Zhao, Kaihua Huang, Qing Xie, Li Yang, Yan Xiao, Huimin Zhang
article en
2 citations

Abstract

RC48 plus PD-1 inhibitor for pre-treated advanced G/GEJC patients with HER2 2+/3+ demonstrated superior efficacy than RC48 monotherapy and favourable safety. This combination represents a potential therapeutic strategy, but further large-scale prospective studies are still needed.

Annals of MedicineVol. 57(1)
Sun Yat-sen University (CN), Guangdong Medical College (CN), Nanfang Hospital (CN), Huizhou Central People's Hospital (CN), Sun Yat-sen University Cancer Center (CN), Affiliated Hospital of Guangdong Medical College Hospital (CN), State Key Laboratory of Oncology in South China, Southern Medical University (CN)
Openalex Percentile: Top 8%
Gastric Cancer Management and Outcomes
3.04
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