Accelerating AI innovation in healthcare: real-world clinical research applications on the Mayo Clinic Platform
Artificial intelligence (AI) holds promise for healthcare, but real-world implementation remains difficult. The Mayo clinic platform (MCP) addresses this by providing scalable, multi-institutional, de-identified data and analytical tools. Through four research projects, we demonstrate MCP's ability to support efficient cohort identification, AI model development, and real-world evidence generation. MCP enables broader accessibility and standardization compared to institutional EHRs, positioning it as a powerful platform for advancing translational research and precision medicine.
Authors
- Nansu Zong (ORCID: https://orcid.org/0000-0003-0066-9524)
- Ahmed Abdelhameed (ORCID: https://orcid.org/0000-0002-9970-2517)
- R. Larsen (ORCID: https://orcid.org/0009-0001-2605-4643)
- Clark C. Otley (ORCID: https://orcid.org/0000-0001-9712-8956)
- Sivaraman Rajaganapathy (ORCID: https://orcid.org/0000-0003-4582-7274)
- Cui Tao (ORCID: https://orcid.org/0000-0002-4267-1924)
- John Halamka (ORCID: https://orcid.org/0000-0003-2305-6755)
- Mayank Goyal (ORCID: https://orcid.org/0000-0001-9060-2109)
- Jun Feng (ORCID: https://orcid.org/0000-0003-4762-7532)
- Yang Liu (ORCID: https://orcid.org/0000-0003-3800-3533)
- Yue Yu (ORCID: https://orcid.org/0000-0002-0860-6643)
- Xiaodi Li
- Ken Liu (ORCID: https://orcid.org/0000-0002-9736-5828)
- Jianfu Li (ORCID: https://orcid.org/0000-0002-9949-7007)
- Xinyue Hu (ORCID: https://orcid.org/0009-0008-3629-7877)
- Phil Fiero
- Soulmaz Boroumand
- Nilufer Taner
Institutions
- Jacksonville College (US)
- WinnMed (US)
- Mayo Clinic Health System (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- npj Health Systems
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1038/s44401-026-00068-1
- Citations
- 1
- Primary Topic
- Artificial Intelligence in Healthcare
- Type
- article
- Field-Weighted Citation Impact
- 195.93
Funders
- Alzheimer's Association
- National Institutes of Health
- National Institute of General Medical Sciences