Time-Dependent Effects of Normothermic and Mild Hypothermic Cardiopulmonary Bypass on the De Ritis Ratio

Aim: This study aims to comparatively evaluate the effects of normothermic and mild hypothermic cardiopulmonary bypass (CPB) strategies on liver function in coronary artery bypass grafting (CABG) operations through the dynamics of the De Ritis ratio. Methods: This retrospective study included 150 patients who underwent CABG with either normothermic (35–37 °C, n=75) or mild hypothermic (28–34 °C, n=75) CPB. Liver function parameters (AST, ALT, De Ritis ratio, GGT, bilirubin) were assessed at the prebypass, postbypass, and postoperative time points. Statistical analysis was performed using SPSS software, with significance set at p