Progressive Hippocampal Neuroarchitecture Changes in the 5×FAD Alzheimer’s Disease Mouse Model
Our findings suggest a potential relationship between AD-related protein pathology, neuroinflammation, and structural plasticity impairments in the hippocampus. Collectively, these changes may contribute to disrupted synaptic transmission and behavioral deficits associated with AD pathology.
Authors
- BuHyun Youn (ORCID: https://orcid.org/0000-0002-8010-519X)
- Changjong Moon (ORCID: https://orcid.org/0000-0003-2451-0374)
- Hyewon Jang (ORCID: https://orcid.org/0009-0008-3220-7715)
- Sueun Lee (ORCID: https://orcid.org/0000-0002-8179-5137)
- Yeong-Jun Kim
- Yeonghoon Son (ORCID: https://orcid.org/0000-0001-7948-2599)
- Joong‐Sun Kim (ORCID: https://orcid.org/0000-0003-2180-4860)
- Jeongmin Lee (ORCID: https://orcid.org/0000-0002-4535-2312)
- Sang-Won Kim
- Jong‐Hwan Park (ORCID: https://orcid.org/0000-0003-4664-5640)
Institutions
- Chonnam National University (KR)
- Konkuk University (KR)
- Korea Institute of Oriental Medicine (KR)
- Korea Institute of Radiological and Medical Sciences (KR)
- Pusan National University (KR)
Publication Details
- Journal
- Journal of Integrative Neuroscience
- Published
- 2025-09-29
- DOI
- https://doi.org/10.31083/jin40831
- Citations
- 3
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.49