Argon Alleviates Bone Cancer Pain by Mitigating Neuronal Ferroptosis via the TLR2-COX-2 Pathway
These findings demonstrate that argon effectively mitigates neuronal ferroptosis and alleviates BCP by downregulating the TLR2-COX-2 pathway, highlighting its therapeutic potential for conditions involving ferroptosis, such as cancer-related pain and neurodegenerative diseases.
Authors
- Fuhai Ji (ORCID: https://orcid.org/0000-0001-6649-665X)
- Gujun Cong (ORCID: https://orcid.org/0009-0005-7193-3179)
- Haiyan Sun (ORCID: https://orcid.org/0000-0002-1923-1250)
- Tong Liu (ORCID: https://orcid.org/0000-0001-9152-5264)
- Chao Zhang (ORCID: https://orcid.org/0000-0003-3083-9934)
- Peipei Kang (ORCID: https://orcid.org/0009-0008-9528-2659)
- Yang Zhang (ORCID: https://orcid.org/0000-0002-5786-7452)
- Junyi Ma
- Lei Wang (ORCID: https://orcid.org/0000-0002-0578-150X)
- Xiaowen Meng (ORCID: https://orcid.org/0000-0001-6961-8683)
Institutions
- Nantong University (CN)
- Soochow University (CN)
- Affiliated Hospital of Nantong University (CN)
- Nantong Tumor Hospital (CN)
- Second People's Hospital of NanTong (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-09-25
- DOI
- https://doi.org/10.31083/fbl43761
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article
- Field-Weighted Citation Impact
- 0.00