Sperm DNA Fragmentation in Infertile Men With Varicocele: Clinical Epidemiology and Comparative Assessment of Microsurgical Varicocelectomy and Antioxidant Therapy

This study reveals comparable varicocele prevalence between subfertile (29.5%) and fertile men (27.2%), with impaired semen quality and elevated SDF levels in subfertile cases. Microsurgical varicocelectomy proved most effective, while antioxidant therapy offered a viable alternative or adjunct for non-surgical candidates, underscoring the need for tailored varicocele infertility treatments.

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Publication Details

Journal
Frontiers in Bioscience-Scholar
Published
2025-08-29
DOI
https://doi.org/10.31083/fbs33393
Citations
1
Primary Topic
Sperm and Testicular Function
Type
article
Field-Weighted Citation Impact
1.70
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article

Sperm DNA Fragmentation in Infertile Men With Varicocele: Clinical Epidemiology and Comparative Assessment of Microsurgical Varicocelectomy and Antioxidant Therapy

A.B. Shomarufov, Sh. A. Abbosov, Abdukodir Abdukahharovich Fozilov, Vladimir A. Bozhedomov et al.
1 citations
Frontiers in Bioscience-Scholar
Sperm and Testicular Function
1.70
article

Sperm DNA Fragmentation in Infertile Men With Varicocele: Clinical Epidemiology and Comparative Assessment of Microsurgical Varicocelectomy and Antioxidant Therapy

A.B. Shomarufov, Sh. A. Abbosov, Abdukodir Abdukahharovich Fozilov, Vladimir A. Bozhedomov, Lola Abdurakhimova
article en
1 citations

Abstract

This study reveals comparable varicocele prevalence between subfertile (29.5%) and fertile men (27.2%), with impaired semen quality and elevated SDF levels in subfertile cases. Microsurgical varicocelectomy proved most effective, while antioxidant therapy offered a viable alternative or adjunct for non-surgical candidates, underscoring the need for tailored varicocele infertility treatments.

Frontiers in Bioscience-ScholarVol. 17(3)
Moscow State University (TJ), Tashkent Pediatric Medical Institute (UZ), Westminster International University in Tashkent (UZ)
Openalex Percentile: Top 12%
Sperm and Testicular Function
1.70
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