Cystine and Antibiotic Treatment Alters Low Molecular Weight Thiol Levels in Mycobacterium smegmatis
The mechanisms of cysteine homeostasis under the action of antibiotics in <i>M. smegmatis</i> are similar to those in <i>E. coli</i> and <i>B. subtilis</i>, indicating the universal nature of stress response. The opposing effects of cystine-derived H<sub>2</sub>S on physiological parameters in <i>M. smegmatis</i> and <i>E. coli</i> may be important factors contributing to their susceptibility to antibiotics.
Authors
- Г. В. Смирнова (ORCID: https://orcid.org/0000-0001-6116-8147)
- Oleg N. Oktyabrsky (ORCID: https://orcid.org/0000-0002-9864-209X)
- Lyubov Sutormina (ORCID: https://orcid.org/0000-0002-3242-361X)
- Vadim Ushakov (ORCID: https://orcid.org/0000-0003-3293-7765)
- Aleksey V. Tyulenev (ORCID: https://orcid.org/0000-0002-0312-0409)
- Tatyana Kalashnikova
Institutions
- Institute of Ecology and Genetics of Microorganisms (RU)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-09-25
- DOI
- https://doi.org/10.31083/fbl44441
- Primary Topic
- Sulfur Compounds in Biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00