Abnormal Brain Connectivity Patterns in Children with Global Developmental Delay Accompanied by Cognitive Impairment: A Resting-State EEG Study
Children with GDD exhibit abnormal patterns of brain functional connectivity, characterized by global hypo-connectivity and local hyper-connectivity. Specific network metrics under these abnormal patterns are significantly correlated with cognitive impairment in GDD. This study also highlights the potential of the γ-band characteristic path length as an EEG biomarker for diagnosing GDD.
Authors
- Mingmei Wang (ORCID: https://orcid.org/0000-0003-4689-4700)
- Yonghui Yang (ORCID: https://orcid.org/0000-0001-8165-4003)
- Dengna Zhu (ORCID: https://orcid.org/0000-0003-1399-5812)
- Yi Zhang (ORCID: https://orcid.org/0000-0003-0632-8958)
- Zhichong Hui (ORCID: https://orcid.org/0009-0006-8767-6979)
- Gongxun Chen
- Yan Li (ORCID: https://orcid.org/0000-0002-7465-7705)
- Sansong Li
- Jiaming Kang
- Lei Yang (ORCID: https://orcid.org/0009-0009-1229-4476)
- Guangyu Zhang
- Jiamei Zhang (ORCID: https://orcid.org/0000-0003-1242-5543)
- Kaili Shi (ORCID: https://orcid.org/0000-0002-7584-8298)
- Yanlei Su
- Yuxia Hu
- Weihang Qi
Institutions
- Zhengzhou University (CN)
- Guangxi Zhuang Autonomous Region Brain Hospital (CN)
- Third Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Journal of Integrative Neuroscience
- Published
- 2025-09-30
- DOI
- https://doi.org/10.31083/jin44410
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00