Single-cell Sequencing Analysis Reveals Cell Subtypes With High Expression of Coagulation Factor 3 and Their Possible Roles in Pancreatic Ductal Adenocarcinoma
The high expression of F3 in specific iCAF subtypes suggests a role in PDAC hypercoagulability and tumor progression. Targeting these iCAF subtypes could provide potential strategies for treating PDAC.
Authors
- Lili Wang (ORCID: https://orcid.org/0000-0002-6969-8908)
- Rui Qiao (ORCID: https://orcid.org/0000-0003-3775-8619)
- Chanjuan Cui (ORCID: https://orcid.org/0000-0003-0920-8126)
- Hengwen Gong
- Chunyan Wang (ORCID: https://orcid.org/0000-0002-3913-8192)
- Shengkai Huang (ORCID: https://orcid.org/0000-0001-6702-243X)
- Jun Ma (ORCID: https://orcid.org/0009-0000-7261-7999)
- Mengyao Yu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- National Cancer Center (US)
- Shanxi Provincial Cancer Hospital (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-09-26
- DOI
- https://doi.org/10.31083/fbl44029
- Citations
- 1
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.05