Biological activity of pumpkin pulp extracts: cytoprotection, anti-inflammatory effects, and photoprotection in human skin cells
Significant variations in biological activities among the examined accessions were noted, with <i>C. maxima</i> extracts showing pronounced antioxidant and antiinflammatory properties while <i>C. moschata</i> extract showed the highest SPF values. These findings represent the first report on the skin-beneficial effects of pumpkin pulp extracts, identifying them as sustainable sources of safe, bioactive compounds with antioxidant, anti-inflammatory, and photoprotective properties for dermatological or cosmetic applications.
Authors
- Dragana Dekanski (ORCID: https://orcid.org/0000-0001-8467-4165)
- Sanja Vlaisavljević (ORCID: https://orcid.org/0000-0002-1184-9080)
- Jelena Antić‐Stanković (ORCID: https://orcid.org/0000-0002-0348-4368)
- Dragana D. Božić (ORCID: https://orcid.org/0000-0002-5373-5540)
- Andrea Pirković (ORCID: https://orcid.org/0000-0002-1182-4895)
- Milica Jovanović Krivokuća (ORCID: https://orcid.org/0000-0001-8292-4853)
- Mirjana Nacka-Aleksić (ORCID: https://orcid.org/0000-0003-0750-9347)
- Milorad Miljić (ORCID: https://orcid.org/0000-0002-9278-9330)
- Aleksandra Jovanović (ORCID: https://orcid.org/0000-0001-5394-0125)
- Zanka Bojic-Trbojevic
Institutions
- University of Graz (AT)
- University of Novi Sad (RS)
- University of Belgrade (RS)
Publication Details
- Journal
- Cutaneous and Ocular Toxicology
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1080/15569527.2025.2570195
- Primary Topic
- Advances in Cucurbitaceae Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00