Chromatin relaxation dynamics and histone PTMs in the early DNA damage response

During cellular proliferation DNA undergoes frequent replication cycles in which errors inevitably accumulate. DNA simultaneously faces continuous damage from endogenous sources [e.g., reactive oxygen species (ROS)] and environmental stressors, such as ultraviolet (UV) and ionizing radiation (IR).

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Publication Details

Journal
Cancer Biology and Medicine
Published
2025-10-09
DOI
https://doi.org/10.20892/j.issn.2095-3941.2025.0369
Primary Topic
DNA and Nucleic Acid Chemistry
Type
article
Field-Weighted Citation Impact
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article

Chromatin relaxation dynamics and histone PTMs in the early DNA damage response

Jinqin Qian, Zhongyi Xie, Wei‐Guo Zhu, Liqun Zhou
Cancer Biology and Medicine
DNA and Nucleic Acid Chemistry
article

Chromatin relaxation dynamics and histone PTMs in the early DNA damage response

Jinqin Qian, Zhongyi Xie, Wei‐Guo Zhu, Liqun Zhou
article en

Abstract

During cellular proliferation DNA undergoes frequent replication cycles in which errors inevitably accumulate. DNA simultaneously faces continuous damage from endogenous sources [e.g., reactive oxygen species (ROS)] and environmental stressors, such as ultraviolet (UV) and ionizing radiation (IR).

Cancer Biology and MedicineVol. 22(11)
Peking University (CN), Peking University First Hospital (CN), Shenzhen University Health Science Center (CN)
Openalex Percentile: Top 75%
DNA and Nucleic Acid Chemistry
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