Impact of Brain‐Derived Neurotrophic Factor (BDNF) Variants on Cardiometabolic Profiles: A Systematic Review and Meta‐Analysis of Coronary Artery Disease and Obesity
The rs6265 variant exerts a modest yet statistically significant influence on cardiometabolic profiles, overweight, obesity, CAD, and depression. Specifically, the rs6265 A allele serves as a protective factor against cardiovascular disease and obesity but appears to be a risk factor for depression in patients with CAD.
Authors
- Wencai Jiang (ORCID: https://orcid.org/0000-0002-1983-5281)
- Xiao Wang (ORCID: https://orcid.org/0000-0002-3673-4044)
- Ya Huang (ORCID: https://orcid.org/0000-0001-7020-8497)
- Yan Mei (ORCID: https://orcid.org/0000-0002-4448-9114)
- Xiaoyan Chen (ORCID: https://orcid.org/0000-0001-8109-4691)
- Qi Long Yi (ORCID: https://orcid.org/0000-0003-3687-735X)
- Zhi Wei Luo
Institutions
- Suizhou Central Hospital (CN)
Publication Details
- Journal
- Obesity Reviews
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1111/obr.70027
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.00