Innovative Strategy for Enhanced Delivery of Anti-Fibrotic miR-150 via PDGFR-Targeted Exosomes for Fibrosis Treatment
The findings highlight the potential of PDGFR-tEx for efficient miR-150 delivery, demonstrating improved therapeutic efficacy with reduced systemic toxicity. This targeted approach may offer a more precise and effective treatment for liver fibrosis, surpassing conventional methods.
Authors
- Tae Ho Hong (ORCID: https://orcid.org/0000-0003-3864-8104)
- Ha‐Eun Hong
- Say‐June Kim (ORCID: https://orcid.org/0000-0001-5171-4837)
- Ho Joong Choi (ORCID: https://orcid.org/0000-0002-0862-098X)
- Ok‐Hee Kim (ORCID: https://orcid.org/0000-0002-9204-2587)
- Jung Hyun Park
Institutions
- Korea Pharma (South Korea) (KR)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Journal of Korean Medical Science
- Published
- 2025-01-01
- DOI
- https://doi.org/10.3346/jkms.2025.40.e294
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81