Autochthonous transmission of extensively drug-resistant Neisseria gonorrhoeae in Germany, 2025
We report four confirmed autochthonously transmitted gonorrhoea cases in Germany in 2025, with <i>Neisseria gonorrhoeae</i> isolates exhibiting high-level azithromycin and cefixime resistance. Regarding ceftriaxone, isolates were susceptible for two cases and resistant for two, rendering the later extensively drug-resistant (XDR-NG). Cases, all heterosexual males, were in their late teens to mid-60s. Three isolates were MLST ST18091, with the mosaic <i>penA</i>-60.001 allele and the 23S rRNA A2045G mutation and were related to an XDR-NG detected in the United Kingdom in 2024.
Authors
- Hana Tlapák
- Regina Selb (ORCID: https://orcid.org/0000-0001-5531-5198)
- Susanne Buder (ORCID: https://orcid.org/0000-0002-5878-7892)
- Dagmar Heuer (ORCID: https://orcid.org/0000-0003-2551-1299)
- Kathleen Klaper
- Klaus Jansen (ORCID: https://orcid.org/0000-0001-8358-6796)
Institutions
- Robert Koch Institute (DE)
Publication Details
- Journal
- Eurosurveillance
- Published
- 2025-10-09
- DOI
- https://doi.org/10.2807/1560-7917.es.2025.30.40.2500738
- Citations
- 1
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 1.18