A sustainable approach to the synthesis of 2-arylimidazo[1,2- <i>a</i> ]pyridines followed by sequential amino and bromo functionalization
We developed a CBr 4 -mediated, sustainable, solvent-free method to synthesize 2-arylimidazo[1,2- a ]pyridines from 2-aminopyridines and acetophenones, enabling one-pot, oxidant-free C3 amino-functionalization and C3 bromo-functionalization using K 2 S 2 O 8 .
Authors
- Gakul Baishya (ORCID: https://orcid.org/0000-0001-6431-6678)
- Mayurakhi Bhuyan (ORCID: https://orcid.org/0000-0002-2069-2476)
- Srinivas Ambala
- R. C. Borah (ORCID: https://orcid.org/0000-0002-1295-3664)
Institutions
- North East Institute of Science and Technology (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- New Journal of Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5nj02726h
- Primary Topic
- Synthesis and Reactivity of Heterocycles
- Type
- article
- Field-Weighted Citation Impact
- 0.00