Pulsed electromagnetic fields preconditioned extracellular vesicles derived from mesenchymal stromal cells prevents necroptosis of osteoblasts in osteonecrosis of the femoral head rats
PEMFs with 3 mT amplitude preconditioned BMSC-EVs could promote bone formation by inhibiting osteoblasts necroptosis via Ripk1-Ripk3-Mlkl signaling in ONFH.
Authors
- Chengqi He (ORCID: https://orcid.org/0000-0002-5349-0571)
- Hongchen He (ORCID: https://orcid.org/0000-0002-3016-022X)
- Jiang-Yin Zhang (ORCID: https://orcid.org/0009-0003-6832-6795)
- Xiang-Xiu Wang
- Xiao-Na Xiang (ORCID: https://orcid.org/0000-0001-8659-1080)
Institutions
- Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.3389/fbioe.2025.1655579
- Citations
- 1
- Primary Topic
- Bone and Joint Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- National Natural Science Foundation of China
- West China Hospital, Sichuan University