The Contribution of BMI to a Young Child’s Risk of Islet Autoimmunity Is Dependent on HLA-DR4-DQ8 Without HLA-DR3-DQ2
The contribution of BMI to risk of IA during early childhood is dependent on the HLA-DR-DQ genotype more so than the first-appearing IA phenotype.
Authors
- Mikael Knip (ORCID: https://orcid.org/0000-0003-0474-0033)
- Riitta Veijola (ORCID: https://orcid.org/0000-0002-6557-270X)
- Teija Mykkänen
- Carin Andrén Aronsson (ORCID: https://orcid.org/0000-0003-0256-9367)
- Tiia Honkanen
- Aubrie Merrell
- Ashok Sharma (ORCID: https://orcid.org/0000-0001-9597-4374)
- Jaakko J. Koskenniemi (ORCID: https://orcid.org/0000-0002-9348-3325)
- David Hadley (ORCID: https://orcid.org/0000-0003-1634-1187)
- Evelyn Tekum Amboh
- Karin Ottosson
- Stephen Dankyi
- Pieta Kemppainen
- Rajesh Adusumali
- Katharina Warncke (ORCID: https://orcid.org/0000-0003-1758-7656)
- Carina Hansson
- Lina Fransson
- Merja Koskinen
- Cristina McCarthy
- Carina Törn (ORCID: https://orcid.org/0000-0003-2421-2633)
- Andrea K. Steck (ORCID: https://orcid.org/0000-0002-5931-9484)
- Jutta E. Laiho (ORCID: https://orcid.org/0000-0002-5443-4651)
- Kenneth C. Young (ORCID: https://orcid.org/0000-0003-3491-257X)
- Tiina Latva-aho
- Beena Akolkar (ORCID: https://orcid.org/0000-0002-2351-5942)
- Sirpa Anttila (ORCID: https://orcid.org/0009-0004-4806-0800)
- Eric W. Triplett (ORCID: https://orcid.org/0000-0002-1845-4866)
- Dena Tewey
- Kathleen Heyman (ORCID: https://orcid.org/0000-0003-1971-7477)
- Åke Lernmark (ORCID: https://orcid.org/0000-0003-1735-0499)
- Linda Sofia Jonsson (ORCID: https://orcid.org/0000-0002-8110-2855)
- Kyla Chandler (ORCID: https://orcid.org/0000-0001-5587-8724)
- Naghmeh Karimi
- Päivi Tossavainen (ORCID: https://orcid.org/0000-0003-0388-9039)
- Joanna Stock
- Katja Kokkonen
- Sofie Åberg
- Heikki Hyöty (ORCID: https://orcid.org/0000-0003-0370-4145)
- Thomas Briese (ORCID: https://orcid.org/0000-0002-4819-8963)
- Jennifer A Schmidt (ORCID: https://orcid.org/0000-0003-2853-9801)
- Zhian Othmani
- Francisco Perez Laras
- Marian Rewers
- Saori Itoshima (ORCID: https://orcid.org/0000-0002-9800-6747)
- Noah Sulman
- Marlena Maziarz (ORCID: https://orcid.org/0000-0003-1417-6050)
- Irene Viinikangas
- Sarah Stollery
- Erika Trulsson
- Jukka Kero (ORCID: https://orcid.org/0000-0001-8767-7222)
- Marielle Lindström
- Markus Mattila (ORCID: https://orcid.org/0000-0002-7829-9474)
- Marisa Stahl
- Daniel Felipe-Morales
- Zeliha Mestan
- Sandra Baethke
- MaryEllen Dalmagro-Elias Smith
- Katri Lindfors (ORCID: https://orcid.org/0000-0001-7417-5151)
- Sarah Austin-Gonzalez
- Laura Gandolfo
- Christiane Winkler (ORCID: https://orcid.org/0000-0002-7606-3687)
- Steven Meulemans
- Laura Leppänen (ORCID: https://orcid.org/0009-0009-1953-9368)
- Taru Karjalainen
- Teresa Buckner (ORCID: https://orcid.org/0000-0002-5831-1683)
- Hanna Jisser
- Edwin Liu (ORCID: https://orcid.org/0000-0003-3591-8922)
- Emma Nilsson (ORCID: https://orcid.org/0000-0003-0586-8063)
- Eoin McKinney (ORCID: https://orcid.org/0000-0003-3516-3072)
- Ezio E. Bonifacio (ORCID: https://orcid.org/0000-0002-8704-4713)
- Sanna Jokipuu
- Tomi Pastinen (ORCID: https://orcid.org/0000-0003-4016-5021)
- Steffen Ullitz Thorsen (ORCID: https://orcid.org/0000-0003-4783-2931)
- Jessica Melin (ORCID: https://orcid.org/0000-0002-8858-2126)
- Kimberly Bautista
- Shu Liu (ORCID: https://orcid.org/0000-0002-6281-4531)
- Elina Mäntymäki
- Elin M Hård Af Segerstad (ORCID: https://orcid.org/0000-0002-7676-1186)
- Kristian Lynch (ORCID: https://orcid.org/0000-0002-4310-4163)
- Suzanne Bennett Johnson (ORCID: https://orcid.org/0000-0001-5721-7524)
- Jorma Toppari (ORCID: https://orcid.org/0000-0003-2228-334X)
- Tiina Niininen
- Michael J. Toth (ORCID: https://orcid.org/0000-0003-0668-1911)
- Iris Erlund (ORCID: https://orcid.org/0000-0002-0083-1256)
- Åsa Wimar
- Jenny Bremer
- Leena Eklund Karlsson (ORCID: https://orcid.org/0000-0003-2052-0989)
- Sigrid Lenrick Forss
- Martha Butterworth
- Susanne Hyberg
- Jennifer Garmeson
- Jennifer Skidmore (ORCID: https://orcid.org/0000-0002-9619-8781)
- Michael Abbondondolo
- Margaret Franciscus
- Melissa Wroble
- Diane Hopkins (ORCID: https://orcid.org/0000-0002-2390-9909)
- Gertie Hansson
- Steven Fiske
- Jimin Yang (ORCID: https://orcid.org/0000-0002-9829-6916)
- Brigitte I. Frohnert (ORCID: https://orcid.org/0000-0002-6636-4048)
- Ben Kim (ORCID: https://orcid.org/0000-0002-6793-5551)
- Miia Turpeinen (ORCID: https://orcid.org/0000-0002-1420-4632)
- Jennifer Hosford
- Birgitta Janerot-Sjöberg (ORCID: https://orcid.org/0000-0003-1264-1254)
- Maria Markan
- Desmond Schatz (ORCID: https://orcid.org/0000-0002-1044-5762)
- Minna-Liisa Koivikko
- Christina Karges
- William Hagopian (ORCID: https://orcid.org/0000-0003-2979-0475)
- Suvi Μ. Virtanen (ORCID: https://orcid.org/0000-0001-8928-0878)
- Sara Sibthorpe
- Todd M. Brusko (ORCID: https://orcid.org/0000-0003-2878-9296)
- Hemang M. Parikh (ORCID: https://orcid.org/0000-0002-9076-6709)
- Brant Burkhardt (ORCID: https://orcid.org/0000-0002-3780-6644)
- Dorothy Becker
- Randi K. Johnson (ORCID: https://orcid.org/0000-0001-9345-4439)
- Anette Sjöberg
- Terese Wiktorsson
- Lazarus Mramba
- Kendra Vehik (ORCID: https://orcid.org/0000-0001-6243-6772)
- Daniel Agardh
- Emelie Ericson-Hallström
- Marika Korpela
- Michael J. Haller (ORCID: https://orcid.org/0000-0002-2803-1824)
- Anne Wallin
- Minna Romo
- Maria Månsson Martinez (ORCID: https://orcid.org/0000-0002-3320-1226)
- Ponni Vijayakandipan
- Olivia Pearce
- Annika Fors
- Ulla Fält
- Sami Oikarinen (ORCID: https://orcid.org/0000-0003-3901-6774)
- M. F. Rein
- David D Cuthbertson (ORCID: https://orcid.org/0000-0002-3785-9834)
- Richard McIndoe (ORCID: https://orcid.org/0000-0002-3040-3631)
- Belinda Hsiao
- Kalle Kurppa (ORCID: https://orcid.org/0000-0003-4757-2164)
- Marian Rewers (ORCID: https://orcid.org/0000-0003-3829-9207)
- Claudia Ramminger
- Chris Shaffer
- Joanna Gerardsson
- Sibylle Koletzko (ORCID: https://orcid.org/0000-0003-2374-8778)
- Eeva Varjonen
- Sara Rang
- Ulla Uusitalo (ORCID: https://orcid.org/0000-0001-9132-7727)
- Yohanna Nordh
- Fredrik Johansen
- Christopher Eberhard
- Satu Simell
- Noora Nurminen (ORCID: https://orcid.org/0000-0002-6798-7677)
- Jorma Ilonen (ORCID: https://orcid.org/0000-0002-9973-2062)
- Helena Elding Larsson (ORCID: https://orcid.org/0000-0003-3306-1742)
- Corrado Cilio (ORCID: https://orcid.org/0000-0002-2768-740X)
- Lori Ballard
- Sandra Hummel (ORCID: https://orcid.org/0000-0001-6554-5974)
- Annika Adamsson (ORCID: https://orcid.org/0000-0003-1635-0331)
- Sirpa Pohjola
- Thomas Gard
- Caroline Nilsson (ORCID: https://orcid.org/0000-0003-2040-8428)
- Holly O’Donnell
- Maria Lönnrot (ORCID: https://orcid.org/0000-0002-2460-6221)
- Hye Seung Lee (ORCID: https://orcid.org/0000-0002-1667-7986)
- Anna Rosenquist
- Arlene Meyer
- Rasheedah Brown
- Nicholas Cadigan
- Salla Kuusela (ORCID: https://orcid.org/0000-0003-4945-3089)
- Joanna Clasen (ORCID: https://orcid.org/0000-0003-4231-5740)
- Miia Kähönen
- Kathleen M. Gillespie (ORCID: https://orcid.org/0000-0002-3009-8032)
- Emina Halilovic
- Annette Knopff
- Wendy McLeod
- Rachel Karban
- Jenna Rautanen
- Markus Lundgren (ORCID: https://orcid.org/0000-0001-6394-7689)
- Anja Heublein (ORCID: https://orcid.org/0000-0002-1092-2485)
- Michael Killian (ORCID: https://orcid.org/0000-0002-2287-9007)
- Berglind Jónsdóttir (ORCID: https://orcid.org/0000-0003-4129-1767)
- Monika Hansen
- Kobra Rahmati
- Cassandra Remedios (ORCID: https://orcid.org/0000-0002-3915-5339)
- Lu You
- Roswith Roth (ORCID: https://orcid.org/0000-0003-3955-2198)
- Ulla-Marie Carlsson
- Falastin Salami (ORCID: https://orcid.org/0000-0002-0098-4287)
- Jeffrey P. Krischer (ORCID: https://orcid.org/0000-0003-4526-888X)
- Lothar Müller (ORCID: https://orcid.org/0000-0001-9252-4650)
- Kevin Counts
- Juulia Rönkä
- Susanne Dahlberg
- Mirva Koreasalo
- Malin Goldman Tsubarah
- Maija E. Miettinen (ORCID: https://orcid.org/0000-0002-5587-7227)
- Jamie Malloy
- Paula Ollikainen
- Ulrika Ulvenhag
- Olli Simell
- Anita Ramelius (ORCID: https://orcid.org/0000-0003-2407-7785)
- Sören Svensson (ORCID: https://orcid.org/0000-0003-4169-788X)
- Kristian Lynch
- Ingrid Wigheden
- Shreya Roy (ORCID: https://orcid.org/0000-0001-9603-7454)
- Laura M. Jacobsen (ORCID: https://orcid.org/0000-0002-5144-7836)
- Jared Radtke
- Henri Thuma
- Siiri Leisku
- Hanna-Leena Oinas
- Nelli Rönkä
- Hanah Batholomew
- Qian Li (ORCID: https://orcid.org/0000-0001-8827-939X)
- Liping Yu
- Xiang Liu (ORCID: https://orcid.org/0000-0002-0207-2345)
- Ryan Quigley (ORCID: https://orcid.org/0000-0003-4385-6557)
- Mari Vähä-Mäkilä (ORCID: https://orcid.org/0000-0003-2216-4607)
- Rasmus Bennet
- Maryouri Avendano
- Chrystal Yates
- Sari Niinistö (ORCID: https://orcid.org/0000-0003-2041-6241)
- Percy Gordon
- Eva Andersson
- Dongmei Miao
- Marlon Scholz
- Roy Tamura
- Michelle Hoffman
- Zahra Hashmi
- Barbro Lernmark
- Laura Smith
- Melissa Gardiner
- Colleen Maguire
- Silvija Jović
- Mary Beth Klein
- Ashi Daftary
- Anna Hansson
- José Moreno
- Judith Baxter
- Maria Ask
- Patricia Gesualdo
- Jimin Yang
- Anette G. Ziegler (ORCID: https://orcid.org/0000-0002-6290-5548)
- Leena Hakola
- Kathleen Waugh
- Melanie Köger
- Chris Deigan
- Cody McCall
- Elinor Balch
- Veena Gowda
- Jill Norris
- Suvi Ahonen
- Susan Smith (ORCID: https://orcid.org/0000-0003-0639-4242)
- Cigdem Sanverdi
- Rawya Antar
- Magdalena Delikat Kulinski
- Theodosia Massadakis
- Monika Sedig Järvirova
- Ulrika Swartling
- Sanni Heikura
- Noora Ruotsalainen
Institutions
- Turku Centre for Computer Science (FI)
- University of South Florida (US)
- Oulu University Hospital (FI)
- Turku University Hospital (FI)
- TUM Klinikum (DE)
- Center for Environmental Health (US)
- Helmholtz Zentrum München (DE)
- University of Florida (US)
- University of Colorado Health (US)
- National Institute of Diabetes and Digestive and Kidney Diseases (US)
- Skåne University Hospital (SE)
- German Center for Diabetes Research (DE)
- University of Colorado Anschutz Medical Campus (US)
- Indiana University – Purdue University Indianapolis (US)
- Florida College (US)
- University of Oulu (FI)
Publication Details
- Journal
- Diabetes Care
- Published
- 2025-10-09
- DOI
- https://doi.org/10.2337/dc25-1198
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00