One-Year Outcomes After Traumatic Brain Injury and Early Extracranial Surgery in the TRACK-TBI Study
In this cohort study, early EC surgery was associated with adverse function, cognition, and disability after TBI rated as moderate-severe or with radiographic abnormalities on CT scan regardless of GCS at index admission but not after orthopedic trauma or CT- TBI. Further studies may help determine whether surgical timing or other interventions can improve the observed long-term deficits.
Authors
- Michael McCrea
- Jason Barber (ORCID: https://orcid.org/0000-0002-3016-7800)
- Lindsay D. Nelson (ORCID: https://orcid.org/0000-0001-5258-953X)
- David M. Schnyer (ORCID: https://orcid.org/0000-0002-7472-2853)
- Laura B. Ngwenya (ORCID: https://orcid.org/0000-0001-7103-971X)
- Ross Zafonte (ORCID: https://orcid.org/0000-0002-1050-796X)
- Mayur B. Patel (ORCID: https://orcid.org/0000-0001-5230-0871)
- Amelia W. Maiga (ORCID: https://orcid.org/0000-0001-6488-7024)
- Amy J. Markowitz (ORCID: https://orcid.org/0000-0001-9314-2814)
- Richard B. Rodgers (ORCID: https://orcid.org/0000-0002-4101-4172)
- C. Dirk Keene (ORCID: https://orcid.org/0000-0002-5291-1469)
- Ramesh Grandhi (ORCID: https://orcid.org/0000-0001-9000-6083)
- Ava M. Puccio (ORCID: https://orcid.org/0000-0003-2569-9607)
- CJ Roberts (ORCID: https://orcid.org/0000-0003-0889-8567)
- Alex B. Valadka (ORCID: https://orcid.org/0000-0003-0156-1531)
- Vijay Krishnamoorthy (ORCID: https://orcid.org/0000-0002-1365-4121)
- Brandon Foreman (ORCID: https://orcid.org/0000-0002-5418-674X)
- Sabrina R. Taylor (ORCID: https://orcid.org/0000-0003-4867-1922)
- Claudia Sue Robertson (ORCID: https://orcid.org/0000-0002-8509-678X)
- Geoffrey T. Manley (ORCID: https://orcid.org/0000-0002-0926-3128)
- John K. Yue (ORCID: https://orcid.org/0000-0001-9694-7722)
- Nancy R. Temkin
- Christine Mac Donald
- Randall E. Merchant
- Ann-Christine Duhaime
- Ruturaj Vala
Institutions
- Boston Children's Hospital (US)
- University of Pittsburgh (US)
- Duke University (US)
- University of California, San Francisco (US)
- Baylor College of Medicine (US)
- Virginia Commonwealth University (US)
- University of Washington (US)
- Medical College of Wisconsin (US)
- University of Utah (US)
- Massachusetts General Hospital (US)
- VA Tennessee Valley Healthcare System (US)
- Milwaukee VA Medical Center (US)
- Indiana Spine Group (US)
- Neurological Surgery (US)
- University of Cincinnati (US)
- The University of Texas at Austin (US)
- The University of Texas Southwestern Medical Center (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-10-10
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.37271
- Citations
- 1
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 1.39