Search-optimized quantization in biomedical ontology alignment

In the fast-moving world of AI, as organizations and researchers develop more advanced models, they face challenges due to their sheer size and computational demands. Deploying such models on edge devices or in resource-constrained environments adds further challenges related to energy consumption, memory usage and latency. To address these challenges, emerging trends are shaping the future of efficient model optimization techniques. From this premise, by employing supervised state-of-the-art transformer-based models, this research introduces a systematic method for ontology alignment, grounded in cosine-based semantic similarity between a biomedical layman vocabulary and the Unified Medical Language System (UMLS) Metathesaurus. It leverages Microsoft Olive to search for target optimizations among different Execution Providers (EPs) using the ONNX Runtime backend, followed by an assembled process of dynamic quantization employing Intel Neural Compressor and IPEX (Intel Extension for PyTorch). Through our optimization process, we conduct extensive assessments on the two tasks from the DEFT 2020 Evaluation Campaign, achieving a new state-of-the-art in both. We retain performance metrics intact, while attaining an average inference speed-up of 20x and reducing memory usage by 70%.

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Publication Details

Journal
Frontiers in Artificial Intelligence
Published
2025-10-10
DOI
https://doi.org/10.3389/frai.2025.1662984
Primary Topic
Biomedical Text Mining and Ontologies
Type
article
Field-Weighted Citation Impact
0.00

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article

Search-optimized quantization in biomedical ontology alignment

Natalia Grabar, Oussama Bouaggad
Frontiers in Artificial Intelligence
Biomedical Text Mining and Ontologies
article

Search-optimized quantization in biomedical ontology alignment

Natalia Grabar, Oussama Bouaggad
article en

Abstract

In the fast-moving world of AI, as organizations and researchers develop more advanced models, they face challenges due to their sheer size and computational demands. Deploying such models on edge devices or in resource-constrained environments adds further challenges related to energy consumption, memory usage and latency. To address these challenges, emerging trends are shaping the future of efficient model optimization techniques. From this premise, by employing supervised state-of-the-art transformer-based models, this research introduces a systematic method for ontology alignment, grounded in cosine-based semantic similarity between a biomedical layman vocabulary and the Unified Medical Language System (UMLS) Metathesaurus. It leverages Microsoft Olive to search for target optimizations among different Execution Providers (EPs) using the ONNX Runtime backend, followed by an assembled process of dynamic quantization employing Intel Neural Compressor and IPEX (Intel Extension for PyTorch). Through our optimization process, we conduct extensive assessments on the two tasks from the DEFT 2020 Evaluation Campaign, achieving a new state-of-the-art in both. We retain performance metrics intact, while attaining an average inference speed-up of 20x and reducing memory usage by 70%.

Frontiers in Artificial IntelligenceVol. 8
Centre National de la Recherche Scientifique (FR), Université de Lille (FR), Savoirs, Textes, Langage (FR), Centre de Recherche en Informatique (FR)
Université de Lille, Centre National de la Recherche Scientifique
Openalex Percentile: Top 75%
Biomedical Text Mining and Ontologies
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