Limited genomic diversity and convergent adaptation of Brucella melitensis isolated from human in East China, from 2011 to 2024
The human brucellosis in Jiangsu is mainly attributed to imported infections through various patterns, which is consistent with the typical epidemiology characteristics observed in low-endemic regions. The identification of four novel cgSTs and evidence of genomic evolutionary changes provide important insights to strengthen surveillance and guide targeted control strategies for brucellosis in East China.
Authors
- Wei Zhang (ORCID: https://orcid.org/0000-0001-5292-7308)
- Jingxin Li (ORCID: https://orcid.org/0000-0001-7370-703X)
- Baohong Xu (ORCID: https://orcid.org/0000-0003-0755-8819)
- Wei-Zhong Zhou (ORCID: https://orcid.org/0000-0001-8013-5607)
- Changjun Bao (ORCID: https://orcid.org/0000-0002-0546-1338)
- Nan Zhang (ORCID: https://orcid.org/0000-0002-0473-4218)
- Ying Zhang (ORCID: https://orcid.org/0000-0002-6505-4822)
- Lu Zhou (ORCID: https://orcid.org/0000-0002-0568-0258)
- Lan Huang (ORCID: https://orcid.org/0000-0001-9594-4722)
- Jie Hong
- Ke Xu (ORCID: https://orcid.org/0000-0003-3812-8619)
- Zhongming Tan (ORCID: https://orcid.org/0000-0003-2731-7668)
- Hai Jiang
Institutions
- Nanjing Agricultural University (CN)
- Nanjing Drum Tower Hospital (CN)
- Jiangsu Provincial Center for Disease Control and Prevention (CN)
- National Institute for Communicable Disease Control and Prevention (CN)
- Southeast University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-10-10
- DOI
- https://doi.org/10.3389/fmicb.2025.1663555
- Primary Topic
- Brucella: diagnosis, epidemiology, treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Jiangsu Province
- Centers for Disease Control and Prevention