Radioactive iodine for differentiated thyroid carcinoma

RAI in DTC is evolving towards a risk-adapted model. Escalating evidence indicates that RAI may be safely withheld in a large proportion of low-risk DTC. Optimal management of intermediate-risk DTC remains controversial, due to heterogeneity in clinical and pathological characteristics and conflicting data over survival advantage. Well designed studies incorporating molecular genotype may be key in identifying those most likely to benefit from RAI and in elucidating mechanisms of RAI-resistance.

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Publication Details

Journal
Current Opinion in Endocrinology Diabetes and Obesity
Published
2025-10-03
DOI
https://doi.org/10.1097/med.0000000000000932
Citations
1
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.29
Controls
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article

Radioactive iodine for differentiated thyroid carcinoma

Saumya Sunny, David Colville, Kathryn Graham, Julie Hephzibah
1 citations
Current Opinion in Endocrinology Diabetes and Obesity
Thyroid Cancer Diagnosis and Treatment
1.29
article

Radioactive iodine for differentiated thyroid carcinoma

Saumya Sunny, David Colville, Kathryn Graham, Julie Hephzibah
article en
1 citations

Abstract

RAI in DTC is evolving towards a risk-adapted model. Escalating evidence indicates that RAI may be safely withheld in a large proportion of low-risk DTC. Optimal management of intermediate-risk DTC remains controversial, due to heterogeneity in clinical and pathological characteristics and conflicting data over survival advantage. Well designed studies incorporating molecular genotype may be key in identifying those most likely to benefit from RAI and in elucidating mechanisms of RAI-resistance.

Current Opinion in Endocrinology Diabetes and ObesityVol. 32(6)
Christian Medical College, Vellore (IN), Beatson West of Scotland Cancer Centre (GB), Glasgow Royal Infirmary (GB), Christian Medical College (IN)
Openalex Percentile: Top 15%
Thyroid Cancer Diagnosis and Treatment
1.29
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