Photosensitive small intestinal submucosal hydrogels loaded with the KR-12-a5 peptide promote periodontal osteogenesis and antimicrobial activity
The IA/SIS/KR-12-a5 hydrogel exhibited rapid UV-induced gelation, strong mechanical properties, antibacterial efficacy, and significant osteogenic potential. These attributes suggest its suitability as an injectable biomaterial for bone regeneration and repair.
Authors
- Bo Kou (ORCID: https://orcid.org/0000-0001-7986-1601)
- Kexin Chang (ORCID: https://orcid.org/0009-0001-0316-1809)
- Keying Chen (ORCID: https://orcid.org/0009-0007-9576-5952)
- Rui Li (ORCID: https://orcid.org/0000-0001-6051-4204)
- Le Li (ORCID: https://orcid.org/0000-0002-9340-9061)
- Shiqing Ma (ORCID: https://orcid.org/0000-0003-1551-8948)
- Fuli Liu (ORCID: https://orcid.org/0000-0001-6320-5132)
- Mengzhen Cui
- Qiquan Yan
- Yazhuo Ni
- Bo Xu
- Yaoyang Li
Institutions
- Shizuoka City Shimizu Hospital (JP)
- Second Hospital of Tianjin Medical University (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-10-10
- DOI
- https://doi.org/10.1186/s12951-025-03601-w
- Citations
- 3
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 4.40