Cutaneous Pseudolymphomas of the Scalp Secondary to Lamotrigine

We present a case of a 25-year-old woman with bipolar disorder that developed five asymptomatic, enlarging scalp nodules over nine months while on a stable dose of lamotrigine. A biopsy revealed mixed B-cell and T-cell lymphocytic infiltrates, and after self-tapering the medication, the lesions shrank. The patient was switched to lurasidone, leading to complete resolution of the scalp nodules. This case supports lamotrigine-induced cutaneous pseudolymphoma, a rare but reversible condition, and emphasizes the need for clinicians to consider drug-induced pseudolymphoma.