Mendelian Randomization Analyses Reveal the Causal Effect of Cathepsin Z on the Risk of Different Subtypes of Thyroid Cancer

Our MR analysis suggests a causal role of cathepsin Z in the development of PTC, offering valuable insights for future mechanistic studies and potential clinical applications targeting cathepsin-mediated pathways in cancer.

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Publication Details

Journal
International Journal of Endocrinology
Published
2025-01-01
DOI
https://doi.org/10.1155/ije/9916769
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Mendelian Randomization Analyses Reveal the Causal Effect of Cathepsin Z on the Risk of Different Subtypes of Thyroid Cancer

Shao-Kun Sun, Jiaxi Yuan
International Journal of Endocrinology
Genetic Associations and Epidemiology
article

Mendelian Randomization Analyses Reveal the Causal Effect of Cathepsin Z on the Risk of Different Subtypes of Thyroid Cancer

Shao-Kun Sun, Jiaxi Yuan
article en

Abstract

Our MR analysis suggests a causal role of cathepsin Z in the development of PTC, offering valuable insights for future mechanistic studies and potential clinical applications targeting cathepsin-mediated pathways in cancer.

International Journal of EndocrinologyVol. 2025(1)
Jiangsu University (CN), First People's Hospital of Kunshan (CN)
Openalex Percentile: Top 69%
Genetic Associations and Epidemiology
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Mendelian Randomization Analyses Reveal the Causal Effect of Cathepsin Z on the Risk of Different Subtypes of Thyroid Cancer — Shao-Kun Sun, Jiaxi Yuan · International Journal of Endocrinology (2025) | TGRS Research Map | TGRS