Monosomy 3 Prediction by Clinical Features and BAP1 Staining and Its Value When Integrated in Liverpool Uveal Melanoma Prognosticator Online (LUMPO3)
M3 can be accurately predicted using clinical and histopathological features, of which nBAP1-IHC is the most significant predictor. The predicted-M3-based LUMPO3 and the genetic-M3-based LUMPO3 are highly consistent in terms of survival prognostication and surveillance planning.
Authors
- Rumana Hussain (ORCID: https://orcid.org/0000-0001-8208-5009)
- Bertil Damato (ORCID: https://orcid.org/0000-0003-1878-7131)
- Antonio Eleuteri (ORCID: https://orcid.org/0000-0003-0718-6672)
- Sarah E. Coupland (ORCID: https://orcid.org/0000-0002-1464-2069)
- Helen Kalirai (ORCID: https://orcid.org/0000-0002-4440-2576)
- Heinrich Heimann (ORCID: https://orcid.org/0000-0002-3298-4644)
- Hung‐Da Chou (ORCID: https://orcid.org/0000-0002-1561-3059)
Institutions
- University of Liverpool (GB)
- Chang Gung University (TW)
- Royal Liverpool University Hospital (GB)
- Chang Gung Memorial Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
- S:t Eriks Ögonsjukhus (SE)
- Moorfields Eye Hospital (GB)
- University College London (GB)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1167/iovs.66.13.17
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chang Gung Medical Foundation