Utility of peritoneal fluid for multiplexed mRNA profiling of peritoneal metastasis from pancreatic cancer
Our data indicate that PF from PM-PC patients is suitable for transcriptomic analysis. Numerous upregulated mRNAs known to play a role in tumour progression were identified. Our data indicate that mRNA profiling may be a clinically useful tool for further prognostic stratification of patients with proven PM, but larger studies are needed to validate our findings.
Authors
- Alan Patrick Ainsworth (ORCID: https://orcid.org/0000-0001-8922-8877)
- Mark Burton (ORCID: https://orcid.org/0000-0002-3782-5933)
- Line Schmidt Tarpgaard (ORCID: https://orcid.org/0000-0001-8505-2544)
- Michael Bau Mortensen (ORCID: https://orcid.org/0000-0002-7270-5005)
- Lea Lecanda Mariager Jakobsen
- Per Pfeiffer (ORCID: https://orcid.org/0000-0002-2925-0586)
- Martin Graversen (ORCID: https://orcid.org/0000-0001-5719-4916)
- Claus Wilki Fristrup (ORCID: https://orcid.org/0000-0003-2721-0967)
- Sönke Detlefsen (ORCID: https://orcid.org/0000-0002-9466-2333)
- Sharuya Kulatheivam
Institutions
- University of Southern Denmark (DK)
- Odense University Hospital (DK)
Publication Details
- Journal
- Pathology - Research and Practice
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1016/j.prp.2025.156250
- Citations
- 1
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.05