FBXW7 Protects against Diabetic Nephropathy by Targeting Metadherin for Ubiquitin Degradation
These findings highlight the protective role of FBXW7 in DN by downregulating Mtdh and indicate that FBXW7 represents a promising therapeutic target for DN.
Authors
- Fenfen Peng (ORCID: https://orcid.org/0000-0003-2737-1971)
- Haibo Long (ORCID: https://orcid.org/0000-0001-6507-2847)
- Zhe Zhang (ORCID: https://orcid.org/0000-0001-6753-4427)
- Xiaowen Chen (ORCID: https://orcid.org/0000-0002-0313-6363)
- Qiyan Chen (ORCID: https://orcid.org/0000-0001-9072-2135)
- Wenting Wu (ORCID: https://orcid.org/0000-0003-3764-0063)
- Yaozhong Kong (ORCID: https://orcid.org/0000-0002-9178-6023)
- Ruiling Tang
- Congwei Luo
Institutions
- First People's Hospital of Foshan (CN)
- Zhujiang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Kidney Diseases
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1159/000547922
- Primary Topic
- Cancer Mechanisms and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Southern Medical University
- Basic and Applied Basic Research Foundation of Guangdong Province