Risk factors and clinical consequences of interval cancers arising within faecal immunochemical testing-based colorectal cancer screening programme
Patients with interval CRCs and a detectable faecal immunochemical test result below the predetermined threshold appear to be significantly disadvantaged with respect to stage at presentation and survival. Almost half of interval CRCs diagnosed within 2 years had detectable haemoglobin on screening faecal immunochemical test and would be a target for lower positivity thresholds.
Authors
- Yasuko Maeda (ORCID: https://orcid.org/0000-0002-4081-4741)
- Alastair Thomson (ORCID: https://orcid.org/0000-0001-6666-1088)
- Malcolm G. Dunlop (ORCID: https://orcid.org/0000-0002-3033-5851)
- Evropi Τheodoratou (ORCID: https://orcid.org/0000-0001-5887-9132)
- Farhat V N Din (ORCID: https://orcid.org/0000-0001-5466-8282)
- Adam Daniel Gerrard (ORCID: https://orcid.org/0000-0001-5649-9240)
- Roberta Garau
Institutions
- NHS Lothian (GB)
- Western General Hospital (GB)
- Edinburgh Cancer Research (GB)
- Centre for Global Health Research (CA)
- Queen Elizabeth University Hospital (GB)
- Institute of Genetics and Cancer (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- BJS Open
- Published
- 2025-09-08
- DOI
- https://doi.org/10.1093/bjsopen/zraf096
- Citations
- 1
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Bowel Cancer UK
- Cancer Research UK
- Royal College of Surgeons of Edinburgh