hsa-miR-144-3p and hsa-miR-4262 are exosomal biomarkers and function as tumor suppressors in HCMV positive brain tumor

Data analysis showed significant deregulation of hsa-miR-144-3p (p < 0.0001), hsa-miR-4262 (p < 0.0001), PI3K (p < 0.0001), and AKT (p < 0.0001) in brain tumor patients. Conclusions: ROC curve analysis showed that deregulation of hsa-miR-144-3p, hsa-miR-4262, PI3K, and AKT may act as good diagnostic markers for brain tumor patients.

Authors

Mahmood Akhtar Kayani (ORCID: https://orcid.org/0000-0001-9886-180X)
Azhar Mehmood (ORCID: https://orcid.org/0000-0002-8094-7557)
Muhammad Haris (ORCID: https://orcid.org/0000-0003-1699-6191)
Ishrat Mahjabeen (ORCID: https://orcid.org/0000-0002-6392-672X)
Muhammad Zahid Hussain

Institutions

COMSATS University Islamabad (PK)
Nishtar Medical College and Hospital (PK)
Institute of Medical Sciences (IN)

Publication Details

Journal: Future Oncology
Published: 2025-10-10
DOI: https://doi.org/10.1080/14796694.2025.2569097
Primary Topic: Extracellular vesicles in disease
Type: article
Field-Weighted Citation Impact: 0.00

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article

hsa-miR-144-3p and hsa-miR-4262 are exosomal biomarkers and function as tumor suppressors in HCMV positive brain tumor

Mahmood Akhtar Kayani, Azhar Mehmood, Muhammad Haris, Ishrat Mahjabeen et al.

Oct 10, 2025

Future Oncology

Extracellular vesicles in disease

article

hsa-miR-144-3p and hsa-miR-4262 are exosomal biomarkers and function as tumor suppressors in HCMV positive brain tumor

Mahmood Akhtar Kayani, Azhar Mehmood, Muhammad Haris, Ishrat Mahjabeen, Muhammad Zahid Hussain

October 10, 2025article en

Abstract

Data analysis showed significant deregulation of hsa-miR-144-3p (p < 0.0001), hsa-miR-4262 (p < 0.0001), PI3K (p < 0.0001), and AKT (p < 0.0001) in brain tumor patients. Conclusions: ROC curve analysis showed that deregulation of hsa-miR-144-3p, hsa-miR-4262, PI3K, and AKT may act as good diagnostic markers for brain tumor patients.

Future OncologyVol. 21(26)

COMSATS University Islamabad (PK), Nishtar Medical College and Hospital (PK), Institute of Medical Sciences (IN)

Openalex Percentile: Top 75%

Extracellular vesicles in disease

DOI Source OpenAlex

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hsa-miR-144-3p and hsa-miR-4262 are exosomal biomarkers and function as tumor suppressors in HCMV positive brain tumor — Mahmood Akhtar Kayani, Azhar Mehmood, et al. · Future Oncology (2025) | TGRS Research Map | TGRS