Inhibiting Monocyte Migration Reduces Arterial Thrombosis and Facilitates Thrombolysis
CCR2 antagonism decreases platelet aggregation and reduces FXIII levels in blood and monocytes, thus driving arterial thrombosis towards the generation of a relatively small, porous, more lysable clot.
Authors
- Marvin Krohn-Grimberghe (ORCID: https://orcid.org/0000-0002-5753-7330)
- Dong‐Eog Kim (ORCID: https://orcid.org/0000-0002-9339-6539)
- Matthias Nahrendorf (ORCID: https://orcid.org/0000-0002-4021-1887)
- H.-Y. Kim (ORCID: https://orcid.org/0009-0008-6522-6488)
- Sebastian Cremer (ORCID: https://orcid.org/0000-0002-6409-9279)
- Dawid Schellingerhout (ORCID: https://orcid.org/0000-0003-3659-435X)
- Hee Jeong Jang (ORCID: https://orcid.org/0000-0003-3048-8636)
- Eo Jin Kim (ORCID: https://orcid.org/0000-0002-6570-264X)
- Jinyong Chung (ORCID: https://orcid.org/0000-0001-9473-5152)
- Jiwon Kim (ORCID: https://orcid.org/0000-0001-6748-7624)
- Taesu Kim
Institutions
- Goethe University Frankfurt (DE)
- Kia Motors (South Korea) (KR)
- The University of Texas MD Anderson Cancer Center (US)
- Dongguk University (KR)
- Gordon Center for Medical Imaging (US)
- Massachusetts General Hospital (US)
- Dongguk University Ilsan Hospital (KR)
- Universitätsklinikum Würzburg (DE)
- German Centre for Cardiovascular Research (DE)
- University Hospital Frankfurt (DE)
- Cardio-Pulmonary Institute (DE)
- Center for Systems Biology (US)
Publication Details
- Journal
- Stroke
- Published
- 2025-10-10
- DOI
- https://doi.org/10.1161/strokeaha.125.052352
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00